What is Dysport??

Prescription Dysport is an injection used to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults less than 65 years of age.

Dysport is a purified formulation that has been shown to deliver temporary improvements in moderate to severe frown lines, even with repeat treatments. So, the effect of repeat treatment with Dysport may be comparable to your first use.*

*In clinical trials, the efficacy of Dysport was studied in a total of 376 patients and was demonstrated with up to 4 repeated treatments. The safety of Dysport has been studied in up to 12 repeated treatments.

Frown lines 101: What causes them?

Over time, repeated movement of the facial skin by the muscles forms frown lines between the eyebrows.

Wrinkles are not only age related. Frown lines are “dynamic”—they happen because of the way a person’s face moves. Because frown lines are created by facial movements such as frowning or squinting, they may develop even in younger adults. Dysport is used to treat moderate to severe frown lines in adult patients less than 65 years of age.

The muscles above and between the eyebrows contract and tighten, and can cause wrinkles. Dysport blocks the nerve signal that causes these facial muscles to contract. This ultimately results in a localized reduction of muscle activity in the treated area and temporarily stops the contraction of these muscles.

How does Dysport work?

With just 1 injection into each of 5 points between and above the eyebrows, Dysport stops the signal from the nerve to the muscles, ultimately resulting in a reduction of muscle activity and temporarily preventing contraction of the muscles that cause frown lines.

Injection sites for Dysport

The untreated facial muscles still contract normally, allowing you to freely show facial expressions, such as smiling, in untreated areas.

You should not be treated with Dysport more frequently than every 90 days.

Dysport dimensions

No downtime: With Dysport, there is little to no downtime after injection. Ask your doctor about any precautions you should take after your treatment. Call your doctor or get medical help right away if you have any problems swallowing, speaking, or breathing. If this happens, do not drive a car, operate machinery, or do other dangerous activities. 

Repeatable results: In clinical trials, the efficacy of Dysport was demonstrated with up to 4 repeated treatments. You should wait at least 90 days between treatments. The safety of Dysport has been studied in up to 12 repeated treatments.

Worldwide experience: Dysport is used for aesthetic purposes in 36 countries. In U.S. clinical trials, Dysport safety was studied in more than 2400 aesthetic patients. A total of 376 patients were studied for efficacy of the product.

Visible Improvements - Before and after photos

These images are real, unaltered photographs of patients treated with Dysport. Patients were asked to form their worst (maximum) frown for each photograph.

The dose of Dysport is not the same as or interchangeable with the dose of any other botulinum toxin product. The dose of Dysport cannot be compared to the dose of any other botulinum toxin product you may have used.

Dysport Safety
Dysport may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems after treatment with Dysport:

• Problems swallowing, speaking, or breathing. These problems can happen hours to weeks after an injection of Dysport usually because the muscles that you use to breathe and swallow can become weak after the injection. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with Dysport.
• People with certain breathing problems may need to use muscles in their neck to help them breathe. These patients may be at greater risk for serious breathing problems with Dysport.
• Swallowing problems may last for several weeks. People who can not swallow well may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving Dysport have the highest risk of getting these problems.
• Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include:
  • loss of strength and muscle weakness all over the body
  • double vision
  • blurred vision and drooping eyelids
  • hoarseness or change or loss of voice (dysphonia)
  • trouble saying words clearly (dysarthria)
  • loss of bladder control
  • trouble breathing
  • trouble swallowing

History
Though approved in the United States in April 2009, Dysport has a history of use in other countries since 1991. First approved for aesthetic use outside the U.S. in 2001, Dysport has steadily gained in popularity around the world. Today Dysport is marketed and sold for aesthetic use in 36 countries (as of October 2009). With its approval by the U.S. Food and Drug Administration, you, too, may join others worldwide who have been treated with Dysport.

In U.S. clinical studies the most common side effects were nose and throat irritation, headache, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation, and nausea. In some cases, Dysport may cause serious side effects, such as swallowing or breathing problems, that may be life threatening.